The main clinical manifestations were hemorrhage of skin, mucous membrane, internal organs as well as prolongation of clotting time ( CT), prothrombin time ( PT) and simple thromboplastin generation time ( STGT). 主要临床表现为皮肤、粘膜、内脏出血、凝血时间(CT,试管法)、凝血酶原时间(PT),简易凝血活酶生成时间(STGT)延长,但以PT和STGT较敏感。